Pickens was targeted just once in the first half as the Cowboys were held under 100 yards of total offense before the break. He would remain quiet through the third quarter, adding a single catch to his ledger on two additional targets before seeing eight looks in the final frame with the Cowboys in desperation mode. The 11 targets finished second on the team to CeeDee Lamb’s 18 while the 73 yards slightly edged the 70 of Lamb. Pickens remains an upside WR2 ahead of a divisional matchup against the inside-funnel Eagles’ secondary in Week 7.

Williams has now been held to 3.8 yards per carry or fewer in five of six games and 45 yards on the ground or fewer in four of six games, with seven combined touchdowns keeping his fantasy value afloat through the first third of the regular season. Furthermore, Williams has now seen 12 or fewer carries in four of six contests to start the year. The good news is that the Cowboys have no choice but to keep riding Williams until the wheels fall off considering the general lack of depth in the backfield, meaning there are likely to be better days ahead for the veteran back. He gets another middling matchup on the ground against the division rival Eagles in Week 7, where he will be a volume-driven RB2.

Prescott and the Cowboys were completely unable to get anything going prior to the half, managing just 92 yards of total offense while taking a 17-point deficit into the break. They would force a three-and-out to start the third quarter and follow it up with a touchdown drive to get on the board, but a punt and two turnovers on downs left them trailing by 16 until a late score inside of two minutes remaining in the final frame. Prescott’s two interceptions occurred deep in Green Bay territory in the second quarter, removing much needed points from the scoreboard in what was then a tight game. The loss drops the Cowboys to 2-4 and looking up at the Giants for the division lead through a third of the regular season. Prescott will be a back-end QB1 on the road against the division rival Eagles in Week 7.

The Chiefs, with Rashee Rice (hamstring) sidelined, made every effort to force feed Worthy near the line of scrimmage in this one. That resulted in Worthy leading the KC offense in both targets and receiving yards, with a long reception of 19 yards. Most of his Week 6 touches were of the gadget variety. Increased usage should give Worthy a sturdy PPR floor for now. He should be considered a flex play next week against the tough Seattle secondary.

Johnston’s lone catch was a fantastic grab over tight coverage in the fourth quarter. He nearly scored on the play. Even with Ladd McConkey out with a head injury, Johnston did not function as the Chargers’ top wideout, as DeAndre Lambert-Smith led the team with ten targets. Johnston will be nothing more than a deep league flex option going forward. He should not be rostered in most 12-team leagues.

The Chiefs once again leaned hard on the rushing attack, running the ball 24 times while attempting 30 passes on the day. Walker breezed through a lifeless LA defense from start to finish. On many of his carries Walker was not touched until he was five or six yards beyond the line of scrimmage. Walker, who accounted for 19 of the team’s 24 rushing attempts, is perhaps the most important player in fantasy football through Week 6. He’ll be an RB1 in Week 7 against his former mates in Seattle.

Kelce was in and out of the lineup in the first half while dealing with a lingering ankle issue. Though he clearly wasn’t 100 percent, Kelce was second on the team (behind Xavier Worthy) in targets and had a 24-yard catch and run reception in the second half. Kelce, who now has nine catches over his past three games, should see more looks from Patrick Mahomes for as long as Rashee Rice (hamstring) is sidelined. He’ll be a top-15 fantasy play in Week 7 against the Seahawks.

Mahomes had multiple touchdown tosses in every game this season headed into Week 6. Kansas City’s offense didn’t have to do much against a sleepy Chargers offense that could barely move the ball once again on Sunday. The Chiefs leaned on Ken Walker, who went for 128 yards and two touchdowns on the day. With Rashee Rice and Tyquan Thornton out, Mahomes relied heavily on Xavier Worthy and Travis Kelce. Until Rice is back and fully healthy, Mahomes will be more of a top-15 option. He gets the Seahawks in Week 7.

Hampton was his usual plodding self in this one, with a long rush of four yards in another depressing outing for the LA offense. Kimani Vidal, meanwhile had seven rushes for 21 yards and got much of his work in the first quarter. Keaton Mitchell had just two carries and did not catch his lone target. Hampton led the backfield in routes and targets on the day. His diminishing role and his lack of efficiency has made Hampton nothing more than a touchdown-dependent desperation flex option this year. The Chargers have a bye in Week 7.

Herbert’s hellish season continued unabated on Sunday against a Kansas City defense that swamped the beleaguered Bolts quarterback on seemingly every drop back. After throwing exactly one touchdown in each of his first five outings, Herbert didn’t have any against the Chiefs. He had a negative EPA per drop back and was 10 percent below his expected pass rate in the loss. Ladd McConkey was ruled out with a head injury in the first half, further complicating OC Mike McDaniel’s efforts to stop the bleeding for the LA offense. The team’s wideout injuries and the predictability of the offense means Herbert should be dropped in most one-QB fantasy formats ahead of the Chargers’ Week 7 bye week.